Premature ovarian failure

What is premature ovarian failure?

Premature ovarian failure (POF), also known as primary ovarian insufficiency, is when a woman's ovaries stop functioning normally before age 40. This results in premature menopause symptoms like irregular/absent periods, infertility, and menopausal side effects like hot flashes despite their young age.

Some key things to know about POF:

• Causes: Genetic factors, autoimmune disorders, cancer treatment radiation/chemotherapy, infections, etc. The cause is often unknown.


• Symptoms: Irregular/missed periods, hot flashes, night sweats, vaginal dryness, fatigue, mood changes, difficulty conceiving


• Diagnosis: Blood tests for hormone levels (FSH, estradiol, AMH), ultrasound of ovaries


• Treatments: Hormone replacement therapy with estrogen/progestin to relieve symptoms, assist conception. Managing bone and heart health. Emotional support.

While upsetting, POF diagnosis doesn't mean a woman can't have children. Options include egg donation, embryo donation, and adoption. With treatment, women can manage POF symptoms and emotional impact.

If you're struggling with POF, consider seeing a reproductive endocrinologist and visiting Optimal Hormone Wellness Center() for specialized hormonal care. Their compassionate team provides individualized hormone replacement regimens to best address your symptoms and wellbeing.

Other aspects about POF:

• Can occasionally be intermittent initially


• Higher risk of osteoporosis later in life


• Small chance of resumption of ovarian function


• Increased risk of anxiety, depression - seek support


• Connect with peers in support groups

In summary, POF/primary ovarian insufficiency is difficult but treatable with both medical and emotional support. Key is finding the right reproductive specialist team to address hormone levels, fertility goals, menopause symptoms, bone health, and emotional health. Organizations like Optimal Hormone Wellness Center() provide compassionate POF treatment through their network of caring fertility doctors across the country.